Chestnut cultivars grown in the same pedoclimatic conditions and on the same clonal rootstock were characterised with sensory, spectrophotometric, and chromatographic analysis to determine the phytochemical composition and nutraceutical properties. Methods: 1,8-Cineole was tested against carbachol, histamine, K⁺ 80 mM and ovalbumin-induced bronchial contractions in Wistar rat or guinea-pig tissues. Seuls les extraits obtenus par PLE des deux plantes étudiées ont montré une activité anti inflammatoire. The study aimed at evaluating antibacterial and antifungal activity of EOs and composite resin material (CR) modified with EO against oral pathogens. A multivariate approach showed that phenolic acids and tannins were the bioactive classes with the highest discriminating power among different genotypes, and that genotype is a significant variable (p < 0.05).

These effects were nearly comparable to indomethacin (3 mg/Kg, i.p.) A Review on Anti-Inflammatory Activity of Phenylpropanoids Found in Essential Oils. In order to identify the anti-inflammatory compounds in the aqueous distillate, cells treated with the aqueous distillate were analyzed by GC-MS. Aroma compounds identified therein were limonene, linalool and α-terpineol.

The sugars and organic acids were identified as active components inducing this pro-inflammatory effect. Rational use of EO containing eucalyptol can improve the immune function of the respiratory tract and the body immunity, while high dose could have damaging effects, through modifying the phagocytic function of CD8 cells and reducing the proportion of blood B cells, NK cells, and IgA. Group differences were calculated by parametric one-way analysis of variance with Tukey's post-hoc test. Some of the guinea-pigs had been previously sensitized with an intramuscular injection of 5% (w/v) ovalbumin/saline solution. The major components were caryophyllene oxide (15.17%) followed by α-humulene (13.96%), α-copaene (11.75%), (E)-β-caryophyllene (8.44%), and δ-cadinene (6.78%). Chemical compositions of oil were identified by GC/MS. An alternative, unrelated biosynthesis pathway of IPP is known in some bacterial groups and the plastids of plants, the so-called MEP-(2-methyl-D-erythritol-4-phosphate) pathway, which is initiated from C5 sugars. Linalool considerably inhibited NO production (IC50 18 µg/mL). [14] For example, camphor, citral, citronellol, geraniol, grapefruit mercaptan, eucalyptol, ocimene, myrcene, limonene, linalool, menthol, camphene and pinenes are used in perfumes and cosmetic products. inhibited the oedema by 46.90% and 67.83%, respectively. This study investigates the ameliorative effect of Ocimum basilicum essential oil on an acetic acid-induced colitis model in rats. Results: The amount of CD4+ T lymphocytes in the uterus of LPS-induced abortion mice was much higher (P < 0.01) than that of the control mice, but there was no significant difference in the amount of CD4+ T lymphocytes (P > 0.05).

Conclusions: This is the first yet comprehensive scientific report about the chemical compositions and pharmacological properties of the essential oil of A. sessiflora.

reduced granuloma weight by 13.04% and 48.09%. of Nigella sativa L. seeds and its active principle thymoquinone has been examined using carrageenan-induced oedema in rat hind paws and cotton seed pellet granuloma in rats. Monoterpenes are emitted by forests and form aerosols that are proposed to serve as cloud condensation nuclei (CCN). Methods: Lipopolysaccharide (LPS) (0.10 μg/mouse) was injected via the tail vein in order to induce abortion in 7-day-gestation mice which also received quercetin and bornyl acetate at days 4-7 of gestation. Some of these compounds are produced to protect the trees from insect attacks. It is a valuable source for all people engaged in the study of medicinal plants.

have been studied by GC and GC-MS. Forty-one composition of P. abrotonoides Karel. This anti-inflammatory effect on cytokine production in buccal cells by the orange juice aroma component α-terpineol has been shown for the first time. Cinnamon and thyme EOs showed significantly highest antibacterial activity against S. mutans and L. acidophilus among all tested EOs. Study of the pharmacological activity of natural products in the gastrointestinal tract. Enantiomers and racemic mixtures of limonene displayed significantly different 5-lipoxygenase inhibitory activity suggesting stereoselectivity of the enzyme-catalyzed reaction.

[20][21], "Multi-Substrate Terpene Synthases: Their Occurrence and Physiological Significance", "Boreal forests, aerosols and the impacts on clouds and climate", Philosophical Transactions of the Royal Society A, "14 - Toxicological Aspects of Ingredients Used in Nonalcoholic Beverages",, Creative Commons Attribution-ShareAlike License, This page was last edited on 6 November 2020, at 03:02. On the other hand, the maximal relaxant response to 1,8-cineole in carbachol-precontracted rat tracheas was 85.5 ± 5.7% (IC50 = 408.9 (328-5196) μg/ml) compared with 80.2 ± 4.8% (IC50 = 5.1 (4.3-6.1) μg/ml) with phenoterol. Additional rearrangements and oxidations provide compounds such as citral, citronellal, citronellol, linalool, and many others. This study showed that Endostemon tereticaulis essential oil is rich in bioactive compounds. In this review the anti-inflammatory activity of 32 bioactive monoterpenes found in essential oils is discussed. of Nigella sativa seeds may be due to inhibiting the generation of eicosanoids and lipid peroxidation. De plus, un avantage majeur du pulégone a été dégagé au cours de ce projet : sa faible toxicité par rapport à celle du menthol. The results demonstrate a similar inhibition of mediator production by cineole and budesonide at therapeutic concentrations. These results provide a scientific basis for the use of this plant in traditional medicine. Turkey is the biggest exporter of oregano herb and oil to the world markets. The anti-inflammatory activity of the volatile oil (v.o.) In addition, the v.o. Ethanolic extract and essential oil exhibited potential antibacterial activity. 143 0 obj <> endobj Several monoterpenes produced by trees, such as linalool, hinokitiol, and ocimene have fungicidal and antibacterial activities and participate in wound healing. La méthode DES HS-SDME a montré la meilleure efficacité pour l’extraction de terpènes volatils de différentes polarités, températures d’ébullition et masses moléculaire. An investigation was undertaken to determine the 5-lipoxygenase inhibitory activity of aromatic plants traditionally used to treat dermatological pathologies.

The v.o. Guided by ethnobotanical literature and availability from natural sources, the essential oils of Helichrysum odoratissimum (L.) Less., Heteropyxis natalensis Harv. The oil of P. abrotanoides determined by a high content of monoterpens (61.85%) and it is a medicinal herb to treat leishmaniasisin. LTB4, PGE2, and IL-1β were determined by enzyme immunoassay in the culture supernatants.

Thymol also has antiseptic and disinfectant properties. inhibited granuloma formation by 17.64% and 46.86%, while thymoquinone (3 and 5 mg/Kg, i.p.) Inflammation is a normal, protective response to tissue injury caused by physical trauma, noxious chemicals or microbiological agents. Oregano essential oils obtained from the genera Origanum, Thymus, Coridothymus, Thymbra, Satureja and Lippia are rich in carvacrol, a monoterpenic phenol isomeric with thymol. Results: Thirty six compounds representing 98.1% of total oil were identified in the oil of Stachys athorecalyx. Anise and limette EOs showed no antibacterial activity against S. mutans. Only the hexane extract (A) showed some cytotoxic activity against SK-MEL, KB, BT-549, SK-OV-3, LLC-PK1 and VERO cells lines with IC50 between 60 and > 100 µg/mL. The extracts tested did not exhibit antileishmanial activity. The current study described for the first time the antibacterial activity of Endostemon tereticaulis.

Many monoterpenes found in marine organisms are halogenated, such as halomon. Antiinflammatory efficacies of monoterpenes remain still unknown. 165 0 obj <>stream Exposure to whole orange juice and the DM resulted in a decrease in IL-4 and IL-10 formation compared to non-treated control cells. effect of natural products on gastrointestinal transit and in animal models of ulcerative colitis. This review presents an overview of the anti-inflammatory action exerted by phenylpropanoids from essential oils and discusses possible mechanisms of action involved in the anti-inflammatory response, assessed through specific experimental models.

Activity against Trichomonas vaginalis was also undertaken, showing IC50, IC90 and MLC values of 0.016, 0.03 and 0.06% (v/v) respectively, after 48 hours of incubation. The essential oil of Ocimum basilicum was also analyzed by gas chromatography-mass spectrometry (GC/MS). L’ensemble de ces résultats montre l’intérêt de s’intéresser aux molécules bioactives des plantes pour le traitement des douleurs chroniques inflammatoires mais aussi pour le traitement de toute autre maladie. Antioxidant capacity ranged from 9.30 ± 0.39 mmol Fe+2 kg−1 DW (‘Bouche de Bètizac’) to 19.96 ± 1.89 mmol Fe+2 kg−1 DW (‘Garrone Rosso’). Copyright © 2008 by New Century Health Publishers, LLC. The increased level of myeloperoxidase was significantly decreased after treatment with the essential oil of Ocimum basilicum (200 and 400 ml/kg). In the 1960s, the biological activity of terpenoids began to be noticed by humans, but only limited to certain terpenoids. The extracts did not exhibit antimicrobial action.

essants, analgesic, antimicrobial and antiparasitic. All tested EOs exhibited antifungal activity against C. albicans, whereas cinnamon EO showed significantly highest and limette EO significantly lowest activity. Enterococcus faecalis and Pseudomonas aeruginosa were least susceptible to the oil of A. sessiflora, as seen in their MIC and MLC values over 16% (v/v). The aim of this study was to determine whether 1.8-cineole (Soledum) might be suitable for the treatment of bronchial asthma.

Chestnut agrobiodiversity could be intended as strictly associated to the genotype effect and underlines the large variability within the genus Castanea, and therefore, the importance of in farm and ex situ conservation of local germplasm is part of a global strategy aimed at increasing the levels of agrobiodiversity. Also, this species is used as a cooling medicine in the treatment of fevers and as an analgesic in rheumatic pains. Methods: Male rats divided into several groups.

Ces derniers ont été obtenus à partir de deux plantes peu étudiées : le Calamintha nepeta (L.) savi et l’Asarum europaeum (L.). Monoterpenes may be linear (acyclic) or contain rings (monocyclic and bicyclic). h�bbd```b``n �!

In the search for anti-inflammatory activity of monoterpenoids, inhibition of ovine cyclooxygenase-1 and -2 (COX-1 and COX-2) activity by 15 kinds of monoterpenoids (hydrocarbons, alcohols and ketones) with a p-menthane skeleton was investigated. The extracts A, B, and D inhibited NO production and NF- κB activity with IC50 between 32 and 150 µg/mL. In cells treated with the aqueous distillate in higher concentrations, an increased IL-4 and IL-10 formation was analyzed.